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Members can request expedited appeals when treatment is ongoing or when delays could negatively impact health outcomes

While T3 and T4 primarily act on hepatocytes to regulate lipid metabolism, THR expression in HSCs suggests that excessive TH levels may activate these cells, potentially contributing to fibrogenesis in hyperthyroid states ( Growing evidence from clinical and experimental studies has established a significant association between hypothyroidismboth overt and subclinicaland the development and progression of MAFLD in both adult and pediatric populations (33)

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available evidence is limited to a single Phase 2 trial, and access should only be sought through registered clinical trials