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The DPP4 inhibitor washout period of 56 days prior to randomization was included for participants treated with any DPP4 inhibitor at entry into the study in order to discontinue the DPP4 inhibitor treatment

Quality and relevance assessment Study relevance: Each source was evaluated for its relevance to the key themes of the review

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Gradual dosage adjustments and medical supervision often help patients tolerate medication more comfortably