J Clin Endocrinol Metab 97: 121131
Strategies for the oral delivery of peptides are broadly categorized into four methods: (1) permeation enhancers (PEs), (2) nanoparticles, (3) lipid-based drug delivery systems (self-emulsifying drug delivery systems (SEDDS)) or hydrophobic ion-pairing, and (4) microneedle devices
For patients, variability of that magnitude could translate into dramatically different experiences with what appears to be the same medication
Bacteriostatic preservatives like benzyl alcohol inhibit bacterial growth in multi-dose vials, which is essential for maintaining sterility through repeated needle punctures over weeks of use
Injected subcutaneously once a week, it is being developed both as a standalone and possibly also in combination, and has the potential to be a best in class therapy for chronic weight management, type 2 diabetes, and could be expanded to other indications
Since the term ferroptosis was coined in 2012, the number of studies on this form of cell death has exponentially increased [1, 2]
