In the periphery, pre-proglucagon derived peptides, Glucagon-Like Peptide-1 (GLP-1), Glucagon-Like Peptide-2 (GLP-2) and oxyntomodulin (OXM) are involved in a wide variety of physiological functions, including glucose homeostasis, gastric emptying, intestinal growth, insulin secretion as well as the regulation of food intake
These cases collectively suggest a potential link between semaglutide use and the development or exacerbation of depressive symptoms, warranting closer monitoring in clinical practice
Evanoff, B
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