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Sources Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: SURMOUNT-4 PubMed Continued Treatment With Tirzepatide for Maintenance of Weight Reduction Wegovy Prescribing Information FDA Nutritional Priorities to Support GLP-1 Therapy for Obesity Dr

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By activating both GLP-1 and GIP receptors, they tend to produce greater effects on weight loss and metabolic health than single GLP-1 receptor agonists.

Several animal experiments and clinical trials have demonstrated that GLP-1R agonists are more effective in treating or preventing obesity