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All participants received dietary and exercise counselling aiming at 500-kcal deficit per day

Treatment satisfaction and quality-of-life measures

Injection of BDNF fused with a collagen-binding domain (CBD-BDNF) into the lateral ventricle of MCAO rats, promoted neural regeneration and angiogenesis

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These injections can be painful, as the vitamin is injected under the skin (subcutaneously) or into a muscle (intramuscularly)

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