This modulation can also enhance gut barrier function, preventing the translocation of harmful bacteria or their products to the liver, thereby reducing inflammation and hepatic damage
2017;5(1):e000341
It states that the dual GIP and GLP-1 receptor action does not directly suppress thyroid function, and that the changes seen during treatment come instead from the metabolic shift that accompanies weight loss
For the best results, it should be used alongside lifestyle changes, such as healthy eating and regular physical activity
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12-14 In phase III clinical studies in which exenatide was administered concomitantly with metformin, an SU, or metformin plus an SU, 48% of the 483 patients receiving exenatide 10 mcg twice daily reported nausea compared to 18% of the 483 patients receiving placebo