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Although mild gastrointestinal symptoms might occur, severe adverse effects are rare

These include a history of infection, the use of certain drugs, especially TNF- inhibitors, smoking, alcohol, and stress (195, 199)

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In addition, the FoxO4/ectonucleotide pyrophosphatase/phosphodiesterase family member 2 axis and the TRIM21/NRF2 axis can inhibit ferroptosis, thereby alleviating doxorubicin-induced cardiotoxicity

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When DIHEXA binds to this receptor, it activates signaling pathways within neurons, similar to how BDNF would do