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Iron malabsorption can also be due to gastrointestinal disorders of autoimmune etiology (celiac disease, atrophic gastritis, IBD), which are often associated with autoimmune thyroid diseases [59, 60]
Treatment of AR-positive LNCaP prostate cancer cells with the synthetic steroid R1881 induced transcriptional upregulation of glucose transporters (GLUT1, GLUT12) and glycolytic enzymes (HK1/2, and PFKB2), increased glucose uptake, glucose entry into glycolysis, and glucose storage into lipids ( de novo lipogenesis ) ( Enhanced aerobic glycolysis in response to androgen withdrawal is also observed in in vivo models
Biotin metabolism disorders and epilepsy Biotinase deficiency is caused by mutations in the gene encoding biotinase ( BTD gene), with 51% of cases attributed to the homozygous c.98-104del7ins3 mutation, It is an autosomal invisible genetic disorder with an estimated prevalence of about 1 in 60,000, and 20% of patients have a history of parental consanguinity [70]
Riboflavin (Vitamin B2): Helps convert carbohydrates, fats, and proteins into energy
Testosterone (T) Compared with groups A1, 2 and 3, the levels of T were decreased in groups B, C and D, and the difference was statistically significant ( P 0.05)
