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Pegylated forms of Exedin-4 can significantly reduce organ damage caused by sepsis (cecal ligation and puncture model) by decreasing vascular permeability and inhibiting the interaction between leukocytes and endothelial cells (40)

Both compounds also decreased the mass of brown adipose tissue in lean and obese mice, suggesting a broader effect on adipose tissue metabolism [2]

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In fact, in this study, histological images showed the protective role of N

Potent analogues of somatostatin (peptide hormone consisting of 14 amino acids, found in cells of the pancreas as well as in hypothalamic and other gastrointestinal cells) including octreotide (sandostatin) have been developed for the treatment of acromegaly, gigantism, thyrotropinoma, diarrhea and flushing episodes associated with carcinoid syndrome, and diarrhea in patients with vasoactive intestinal peptide-secreting tumors (VIPomas) [33]

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