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In vitro studies on bone cells supported the expression of the conventional GLP-1R in osteoblasts and confirmed that liraglutide, at nanomolar concentrations, promoted osteoblast differentiation and reduced osteoblast apoptosis via activation of the PI3K/Akt/GSK3K, MAPK, and cAMP/PKA/-catenin intracellular pathways [4648]

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Exp Clin Endocrinol Diabetes (2013) 121(04):2348

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(3) Stanley TL, Feldpausch MN, Oh J, Branch KL, Lee H, Torriani M, Grinspoon SK

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