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Description

After packing, the column was washed with buffer containing 20 mM HEPES, pH 7.4, 100 mM NaCl, 10% (v/v) glycerol, 5 M GLP-2, 25 M TCEP, 5 mM MgCl 2 , 1 mM MnCl 2 , 0.1% (w/v) LMNG and 0.02% (w/v) CHS first (10 column volumes), and then with decreased concentrations of detergents 0.03% (w/v) LMNG, 0.01% (w/v) GDN and 0.008% (w/v) CHS (20 column volumes)

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The change of aldosterone concentration was significantly larger after liraglutide than after placebo only in patients with eGFR 60 ml/min/1.73 m 2 , ( 7.3) [95%CI ( 11.7)( 0.2)] and ( 0.3) [95%CI ( 2.2)(3.8)] respectively, ( p = 0.007)

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With the development of assays and methods, additional modes of cell death may be identified in the future

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Safety and efficacy for this formulation have not been evaluated by the FDA

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