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Under its physiological functional state, Prx2 appears as a monomer (active form) of about 2030 kDa and when interacting with H 2 O 2 , Prx2 is oxidized and a disulfide-linked dimmer is formed (inactive form) [73, 77]

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It was discovered in 1977 when researchers isolated it from the brains of rabbits during induced sleep

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