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How GLP-1s Affect Hydration in the Body GLP-1s can impact hydration in a few common ways: Slower stomach emptying (gastric emptying): Helps regulate blood sugar and appetite but can also change how fluids move through your digestive system

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Problems occurred more often in women, and more often in people ages 45-64

similar experimental paradigms have been used previously [12, 13]

Others prefer more dilute solutions for easier dose adjustments during titration

The decision should be made collaboratively between patient and clinician, considering efficacy, safety, administration route, cost, and individual treatment goals, in line with NICE NG28 guidance