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Current evidence supports continuous use for 812 weeks followed by a 4-week washout period to assess sustained metabolic improvements and prevent receptor downregulation

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It can be challenging to achieve and sustain significant weight loss through diet and exercise alone

Jpn J Pharmacol 32, 9991011

The hydrating agent serves a dual purpose, acting both as a stabilizer and an ionizing additive, inhibiting the aggregation or settling of nanoparticles [46]