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Deficiency of vitamin B12 may cause tiredness, weakness, constipation, loss of appetite, weight loss and megaloblastic anemia (a condition when red blood cells become larger in size than normal)

The diabetes trial added a roughly 2 percent A1C reduction at the top arms, which tells you the glucagon component was not sabotaging glucose control

Studies show that 1,000 to 2,000 mcg a day can help with B12 deficiency

Rev da Associacao Med Bras (1992) (2020) 66Suppl 1(Suppl 1):s1724

Effect of oral vitamin B-12 with or without folic acid on cognitive function in older people with mild vitamin B-12 deficiency: a randomized, placebo-controlled trial