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Amelioration of dysfunctional sodium and calcium homeostasis in cardiomyocytes from diabetic hearts is able to reverse cardiac remodeling and counteract the development of diabetic cardiomyopathy (Lee et al., 2019

Though the trial was powered to only detect non-inferiority, the observed (non-significant) hazard ratio for semaglutide vs

Refined carbohydrates: White pasta, white rice, and other low-fibre starches digest quickly and dont provide the same hunger-lowering effect as high-fibre carbohydrates like brown rice and quinoa

Mawe and Hoffman, 2013)

These effects dont last long and are not a sign of lasting harm