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doi: 10.1093/pcp/pch008 54 OtulakK.GarbaczewskaG

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Interaction of FSH and LH with their complementary gonadotropin receptors (i.e., FSHR and LHR) induces downstream signaling that is critical for steroidogenesis, proliferation, and differentiation, and both signal through the cyclic adenosine monophosphate/protein kinase A (cAMP/PKA) pathway to enhance production of E2 and P4 (Figure 2)