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Despite these advances, important questions remain regarding the long-term durability of benefits, the degree of kidney protection independent of glycemic and weight effects, and the optimal integration of these therapies into routine care

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These bioactive compounds contribute to GLP-1 production in several ways: Polyphenols modulate gut microbial composition, enhancing the abundance of SCFA-producing species

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CrossRef Lipid nanosystems for fatty liver therapy and targeted medication delivery: a comprehensive review Chuipeng Liang, Xing Liu, Zihao Sun, Lin Wen, Jijiao Wu, Sanjun Shi, Xiaolian Liu, Nini Luo, Xiaofang Li International Journal of Pharmaceutics.2025