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Apocynin acquires its selective inhibitory capacity of the reactive oxygen species generating NADPH oxidase via metabolic activation by myeloperoxidase (MPO)

10.1016/j.cellsig.2017.01.004 242 XuY.MaH.ShaoJ.WuJ.ZhouL.ZhangZ.et al (2015)

They described treatment selection as individualized according to comorbidity burden, tolerability, and weight-loss goals

Therefore a good idea rises itself that it would be much more reasonable to synthesize the peptide fragment, which was determined by sequencing as N-terminal pentadecapeptide having amino acid sequence: GEPPPGKPADDAGLV, following with pharmacological assessment and comparison of activity

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