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[8] [9] It is worth noting that whilst these strategies support overall metabolic health, they are not substitutes for prescribed medication when clinically indicated

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While it is likely that G s has the potential to influence the affinity of all peptides that bind in the TMD cavity, the specific amino acid sequence of individual peptides impacts complementarity with receptor residues, influencing the stability of interactions and contributing to the degree of allosterically-facilitated TMD closure around the peptide