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Triple therapy with LABA plus LAMA plus inhaled corticosteroids (ICS) may be indicated for GOLD group E if blood eosinophil counts are 300 cells/L or greater

In cells exposed to high levels of oxidative stress, like red blood cells (RBC), up to 10% of the glucose consumption may be directed to the pentose phosphate pathway (PPP) for the production of the NADPH needed for this reaction

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These data indicate that females may be more sensitive to the blood-glucose regulating effects of the GE2 conjugate than males