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These individuals may experience abrupt elevations in alanine aminotransferase (ALT) levels exceeding 1,000 U/L within 14 months of use, often accompanied by autoimmune hepatitis-like features

It may also improve skin health by reducing pigmentation and acne

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The effect of supplements as monotherapy was not evaluated, nor were some useful biomarkers

Furthermore, novel therapeutic strategies are being explored that leverage CSC surface markers in combinationfor example, bispecific antibodies targeting both CD44 and the tumor stroma or CAR-T cells engineered to recognize CSC markers in conjunction with immunosuppressive cues within the TME