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Conversely, Topak et al

As a receptor tyrosine kinase, IGF-IR can activate a couple of tyrosine kinases that have important roles in tumor progression, such as Src, FAK, JAK, RON, and MET [56, 57]

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Deposits of amyloida protein that the body makescould lead to carpal tunnel syndrome (CTS), neuropathy, or other conditions where a nerve is pressed or trapped