With this background, the present concise review article critically recapitulates the recent advances in our understanding of the normal biology of GGT and its significance in disease states
It also functions as an antioxidant, contributing to health in various ways
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Regardless, the possibility that down-regulation of other redox-dependent genes or processes upon p53 stabilization, or in response to other conditions leading to cell cycle arrest, can promote GSH accumulation and inhibition of ferroptosis cannot be excluded
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doi:10.1038/sj.ejcn.1601907 [51] Stumm RE, Thomas MS, Coombes JA, Greenhill J, Hay J