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Riboflavin supplementationby increasing intracellular FAD concentrationcan restore cofactor binding, improve protein folding and subcellular localization, and rescue enzymatic activity, an effect known as the flavin chaperoning or chemical chaperone mechanism (58)
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Glutathione and skin whitening go hand in hand
Int Rev Chem Eng 3:320 Ilyasov I, Beloborodov V, Antonov D, Dubrovskaya A, Terekhov R, Zhevlakova A, Saydasheva A, Evteev V, Selivanova I (2020) Flavonoids with glutathione antioxidant synergy: influence of free radicals inflow
doi: 10.1016/j.fct.2017.10.042
The cells in each plate were pretreated with MK-2206 2HCl for 1 h before the WECP treatments
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