Respirology 25(7):690702
doi: 10.1016/j.ebiom.2017.11.018
[DOI] [Google Scholar] 82.Mirzaei S., Gholami M.H., Zabolian A., Saleki H., Farahani M.V., Hamzehlou S., Far F.B., Sharifzadeh S.O., Samarghandian S., Khan H., et al
This review summarizes the dysbiosis of gut microbiota in kidney disease and elucidates the underlying molecular mechanisms of microbial dysbiosis through a broad spectrum of signaling pathways, such as TGF-/Smad, IB/NF-B, Keap1/Nrf2, phosphatidylinositol-3 kinase (PI3K), and mitogen-activated protein kinases (MAPK), as well as key mediators, such as AHR, NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, and G protein-coupled receptor 43 (GPR43), via alteration of diverse metabolites
Because most existing POAG polygenic risk scores have been derived largely from European-ancestry cohorts, their transferability to other populations remains limited
Global impacts of western diet and its effects on metabolism and health: A narrative review
