The frustration of yo-yo dieting and constant disappointment with the scale can become a thing of the past
The appetite-suppressive effects create a secondary concern: patients taking both drugs may inadvertently restrict calories to unsafe levels, leading to nutrient deficiencies, muscle loss, or metabolic adaptation that undermines long-term weight loss
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Additionally, it enhances the body's ability to burn calories by stimulating insulin release, which helps in using stored fat for energy
In a head-to-head trial, tirzepatide produced an average of 20.2% body weight loss versus 13.7% for semaglutide over 72 weeks, making it the most effective weight loss medication currently approved
En cuanto a los mecanismos, si bien existe una reduccin de la ingesta energtica, esta no explica por completo la magnitud de la prdida ponderal observada