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[4] [5] This multi-receptor activity distinguishes it from earlier agents such as semaglutide or tirzepatide, and is central to understanding why gastrointestinal side effects including sulphur burps and diarrhoea may occur

Cancer In post-menopausal women, obesity is associated with breast cancer, malignant melanoma, and endometrial cancer [31, 32], whilst both older males and females are at increased risk of hepatobiliary (gallbladder and pancreatic), and genitourinary (renal, bladder, uterine, cervical and prostate) cancers [33]

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It further helps inhibit Tyrosinase activity (prevention of severe skin diseases), promotes pheomelanin synthesis, protects skin from harmful UV damage such as tanning and sunburns

Whether you are restarting semaglutide after a break or deciding to stop cold turkey , understanding the withdrawal symptom profile helps you plan an exit strategy if needed