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These receptors sit on the surface of adipocytes (fat cells), and when activated, they trigger a cascade of intracellular signals that ultimately activate hormone-sensitive lipase

10.1074/jbc.r117.791962 J

Over time, that stress can affect nerve tissue and blood vessels

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Animal studies on induced arthritis models document reduced inflammatory cell infiltration and improved limb function scores in BPC-157-treated subjects compared to untreated control groups