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P., Stamler, A., Vered, Y., Vidne, B

2014;99(11):E23259

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The timeline for any such changes would typically follow substantial weight reduction, which may take several months of GLP-1 treatment

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Additionally, there are other systems independent of GPX4 that regulate ferroptosis, such as ferroptosis suppressor protein 1 (FSP1)/ubiquinone (CoQ10) [23], dihydroorotate dehydrogenase (DHODH) [24], GTP cyclohydrolase-1 (GCH1)/tetrahydrobiopterin (BH4) [25], and amino acid oxidase interleukin-4-induced-1/indole-3-pyruvate [26]