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They can also adjust the therapy if necessary by adding other medicines and speeding up and slowing down the fluid flow rate

When plasma and tissue GSH levels decline after supplementation stops, ROS accumulation accelerates

This reaction depends on the catalytic selenocysteine residue of GPX4, which is directly targeted and inactivated by ferroptosis inducers such as RSL3

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PMID 12818476

In preclinical studies, CSPG biosynthesis inhibitors were shown to be efficient for rescuing OPC differentiation in vitro and accelerating remyelination in mice (Lau et al., 2012