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Phase 3 data shows approximately 22-25% weight loss, making it competitive with retatrutide through a completely different mechanism

doi: 10.4049/jimmunol.180.5.3072

The carnitine shuttle offers a means to transport two carbon units to the cytosol without concomitant oxaloacetate production and thus one prediction is that this route might be important for supporting histone acetylation or lipogenesis in cell types that do not engage the non-canonical cycle

Despite their potential relevance, evidence for their natural processing and presentation is missing in most cases 19

Schulthess, J

60 (Suppl 4), 105109 (2009)