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2014;306:R4908

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Receptor Pharmacology in Research Contexts Published non-clinical characterization describes differential activity across the three receptor targets, with reported potency at the GIP receptor exceeding that observed at the glucagon and GLP-1 receptors relative to their endogenous ligands

Two phase II trials - one in a population with obesity (without T2D) [45], and a second in a population with T2D and overweight/obesity [46], have recently been published and their key findings are presented below (Table 1)

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