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Clinical evidence: key trials and outcomes GLP-1 receptor agonists have shown kidney benefits in cardiovascular safety trials, primarily by reducing the onset and progression of albuminuria [62]

However, this study was not limited to lumbar spinal stenosis and included low back pain of differing etiologies

Used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation

The concern regarding an early increase in risk was most prominently highlighted by the SUSTAIN-6 trial, which found that patients undergoing semaglutide treatment exhibited an elevated risk of diabetic retinopathy complications [82]

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Jo SK, Lee WY, Rhee EJ, Won JC, Jung CH, Park CY, Oh KW, Park SW, Kim SW