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Loren Pickart, who isolated GHK-CU in 1973, shows that the peptide increases production of Type I and Type III collagen while simultaneously upregulating matrix metalloproteinases, the enzymes that break down old, damaged collagen

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Competing Interests The authors declare the following competing interests: [Donghoon Kang and Chin-Ju Park] are listed as an inventor on a pending patent application related to A peptide inhibitor for senescent cell elimination, and a use thereof, filed by [Gwangju institute of science and technology] under application number KR10-2024-0086615