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Research interest centres almost entirely on the cysteine thiol

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doi: 10.1017/S0317167100033497 219

While Glu9 of GLP-1 formed strong and persistent hydrogen bond and van der Waals interactions with R190 2 .60 , Y152 1 .47 , and to a lesser extent, Y148 1 .43 , the polar side chain of Gln3 in oxyntomodulin only formed weak and very transient hydrogen bonds with these residues, and van der Waals interactions only with Y148 1 .43 (Movie S1, Supplemental Table 3)