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In addition, excessive NO produced by iNOS leads to cartilage injury by enhancing matrix metalloproteinase (MMP) activity and down regulating proteoglycan and collagen biosynthesis (Lepetsos and Papavassiliou, 2016)

Hsu, J.-L

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The study demonstrated that compared with the control group, the group receiving the micronutrient supplement experienced a significant decrease in the LH/FSH ratio, testosterone, and AMH levels (230)

Minerals Although Lieb and Schmitt (2020) found that the minerals may confer little or no effect in alleviating the ethanolinduced side effects, their significant effects on repression of postalcohol symptoms have been reported by other scientists