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Current AUA guidelines [4] do not explicitly address the effect of GLP-1 RAs on testosterone modulation

doi: 10.1111/j.1365-2133.1995.tb02752.x 39

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Importantly, transcription factors in the main regulatory and auxiliary loops control many downstream circadian clock-related genes and affect a variety of biological activities such as sleep/wake cycle, eating pattern, energy consumption, and glucose metabolism (Takahashi et al., 2008