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Mild nausea or a settling tiredness in the first week can happen that usually fades as your body adapts

Depleted mucosal PG content consequently results in decreased mucus and bicarbonate generation, reduces mucosal blood flow and inhibits cell proliferation, disrupting the integrity of gastric mucosa

doi: 10.3389/fendo.2022.1033479 Received 31 August 2022 Accepted 27 October 2022 Published 17 November 2022 Volume 13 - 2022 Edited by Jianbo Zhou, Beijing Tongren Hospital, Capital Medical University, China Reviewed by Finbarr P

These changes reinforce that the weight loss achieved had meaningful physiological effects, translating into reductions in established cardiometabolic risk factors