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Transcript abundance was quantified with Kallisto, and differentially expressed genes (DEGs) were identified using DESeq2

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Type 2 diabetes with neuropathy: Forty-eight patients with moderate to severe small fiber neuropathy-induced chronic pain received daily subcutaneous injections of ARA-290 at 4 mg or placebo for 28 days

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B12 plays a key role in the normal functioning of the nervous system, the brain and in the formation of the building blocks of every cell in the body