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REDEFINE 2 (Phase 3a, NEJM 2025) Davies et al., n=1,206, 68 weeks, T2D + BMI 27

Int J Mol Sci (2022) 23(2):585

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This review searched literature published between 2005 and 2021 using keywords cytokines, chemokines, protein targets, small molecular metabolites, and epigenetics, and summarizes recent advances in these novel targets

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It acts as a provitamin and is water soluble