fda compounding semaglutide enforcement november 2025 issued 25 warning letters to telehealth companies for false and misleading claims about compounded GLP-1 products. Unlike FDA-approved drugs, these products have not been proven to be safe, effective, or of Compound versions of GLP-1 drugs

Another red flag is unusually low pricing, which may indicate the use of cheap, substandard, or even fake ingredients

It works by acting like natural hormones in your body

This comprehensive approach ensures that patients achieve their weight loss goals in a fashion that is both healthy and sustainable

The expression of NAMPT, the rate-limiting enzyme in the salvage NAD + biosynthetic pathway, decreases with aging and obesity in various organs, including in white and brown adipose tissue, liver, skeletal muscle, hippocampus, and retina [42,47,63,64,65,66]

This effort included issuing a wave of warning letters to telehealth providers and companies promoting compounded GLP-1 products

Early studies suggest retatrutide may lead to more weight loss than current options, with people losing around 24% of their body weight compared to about 21% with Zepbound and 15% with Wegovy