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Tirzepatide long-term data extends through the multi-year SURPASS trial extensions and post-marketing surveillance

Details regarding the hallmark gene set collection are provided in ref

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It promotes mitochondrial fatty acid oxidation and performs other biochemical functions, including acetyl buffering, maintaining sufficient coenzyme A concentrations in mitochondria during anaerobic energy production, stimulating the tricarboxylic acid cycle, and stimulating ATP export from mitochondria during sustained muscle exercise