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What's a typical starting dose
Women tend to lose a higher percentage of their body weight than men on these weight-loss drugs, so that could have skewed our results. The study participants werent required to limit their caloric intake, either
All published data to date is in animal or in vitro models
However, HFD-feeding has been shown to induce alpha-cell hyperplasia prior to the expansion of beta-cell mass in mice (17, 100), and similarly, studies performed in normoglycemic non-human primates demonstrate that alpha-cell mass was more significantly augmented in response to the increased duration and severity of obesity than that of beta-cells (101)
Attempting to save money through extended dosing intervals typically fails because appetite rebound and inconsistent results lead to treatment abandonment or increased medication needs
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