Because its already widely used, its efficacy and safety profile are well-documented, making it a reliable option for many individuals seeking metabolic optimization today
The insulin signaling pathway
Because these medications target separate physiological systems, no metabolic conflict occurs between them
The ability of exendin4 to protect beta cells against endoplasmic reticulum stress was shown to involve PKA (Yusta et al., 2006), with evidence also for a role for PKA in exendin4induced neuronal protection (Wang et al., 2012)
Its CEO, Zachariah Reitano, told The New York Times that his own experience with erectile dysfunction the result of a heart condition was what had inspired the startup
Theres another big caveat, too: theres a lot of people who end up quitting these drugs after about two years