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Morphine administration significantly reduced the frequency but increased the amplitude of small intestinal motility compared to saline-treated controls (Fig

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Reduced GSH levels shown by decreases in this ratioboth in the plasma and intracellularlyreflect intracellular shifts in oxidative burden and are indicative of immune dysfunction and progression of various disease states such as infection, sepsis, and age-related immune system decline ( GSH has also shown promise as a redox-based biomarker for neurodegenerative disease states

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