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Marks first became aware of the challenge of hypoglycemia while working as a trainee in clinical chemical pathology at the National Hospital for Neurology and Neurosurgery and Institute of Neurology in London

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Semaglutide, for example, can reduce HbA1c by up to 1.8% and weight by up to 6.5 kg

Data availability All data used for this paper are publicly available and are provided in the main text and Supplementary Information