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Interpretation of Preclinical Models: Animal and cell models provide valuable mechanistic insights, but: Rodent biology does not always predict human responses

B12 is an extraordinary nutrient

Several technical reasons may explain our distinctive findings, including differences in the microbiome sampling site, the limited n per group, singly housing mice, or the use of highly similar lean, Western, and high-fat diets which systematically exchanged fat content with carbohydrate content

This tailored approach ensures therapy addresses individual needs while monitoring for side effects, making it a safe and effective addition to menopause care

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Eating a good diet is important for optimum health and prevention of chronic disease