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6 A, F 4, 75 = 7.377, p = 0.0005 and B, F 4, 75 = 5.119, p = 0.0132)

6 Perspective: The intersecting burdens of HBV infection, alcohol use, and liver cancer While the oncogenic mechanisms of HBV, including viral DNA integration, chronic liver inflammation, and HBV protein-driven signaling, are well characterized, growing evidence highlights alcohol consumption as a potent and often underrecognized cofactor linked to disease progression

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Both mechanisms of telomere length maintenance, telomerase and ALT activity, are known to co-exist in cancer cells (De Vitis et al 2018